Senior Patient Safety Investigator
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Technology Consulting
Travel Required:
Up to 10%
Clearance Required:
Ability to Obtain Public Trust
What You Will Do:
The Senior Patient Safety Investigator plays a critical role in establishing and operating a national patient safety function capable of managing a high volume of incoming and in‑flight safety complaints while driving systemic learning and long‑term improvement.
This role sits at the “middle” of the patient safety lifecycle—bridging intake and triage with investigation, escalation, closure, and post‑case learning. The individual will apply deep clinical judgment, standardized safety processes, and data‑driven insight to ensure that complaints are addressed consistently, escalated appropriately, and translated into actionable policy and operational improvements.
Intake, Triage & Case Management
Receive and acknowledge patient safety complaints from multiple intake channels (member‑submitted, patient‑submitted, call center, web‑based)
Conduct rapid clinical triage (often within 24 hours) to assess urgency and potential patient risk
Apply standardized risk stratification (high / moderate / low) using defined clinical and operational criteria
Identify duplicate or related complaints and ensure appropriate case linkage
Serve as case owner, maintaining accountability from intake through closure
Investigation & Escalation
Perform clinically grounded investigations, including:
Review of clinical narratives and supporting documentation
Identification of systemic versus isolated issues
Execute defined escalation pathways, including:
Internal leadership notification
Formal inquiries
Referral to MPSC or other oversight bodies as appropriate
Clearly document findings, decisions, and rationale within the case management system
Process & Program Development
Operationalize standardized patient safety workflows while recognizing the unique nature of individual cases
Help define and refine: Triage criteria, escalation thresholds and case closure standards
Support transition strategies for legacy cases, including close‑out approaches and intake of new complaints into modern systems
Learning, Feedback & Policy Improvement
Contribute to formal post‑case feedback loops to identify trends, recurring risks, and systemic gaps
Translate aggregated case insights into: Policy recommendations, Updated guidance and training or communication needs
Support transparency and leadership reporting to strengthen public trust in the OPTN patient safety function
Technology & Data Enablement
Actively use and help shape a case management platform
Ensure accurate, timely documentation to support: Workflow tracking, dashboards and leadership reporting and prevention of cases falling through the cracks
Partner with technology teams to ensure clinical workflows are reflected accurately in system design
Maintain strict compliance with HIPAA, PHI/PII handling, and federal security requirements
What You Will Need:
Registered Nurse (RN) required; advanced clinical leadership experience strongly preferred
10+ years of progressive clinical experience in acute care, perioperative, critical care, transplant, or related high‑acuity environments
Demonstrated experience exercising independent clinical judgment in complex, high‑risk situations
Proven experience in: Patient safety investigations, quality improvement and risk management or compliance.
Ability to assess clinical risk rapidly and consistently across diverse scenarios
Experience balancing standardized processes with case‑specific nuance
Experience working with EHRs and/or case management systems
Ability to adopt and help operationalize new technology platforms
Comfort using dashboards, reports, and structured data to support leadership decision‑making.
What Would Be Nice To Have:
Experience with organ donation, transplant services, or OPO operations
Prior work in federally regulated or oversight environments
Experience standing up new programs, workflows, or operating models
Experience leading or managing multidisciplinary clinical teams
Strong documentation, decision‑making, and escalation skills
Comfort operating in environments with high case volume and competing priorities
Ability to function effectively with limited external resourcing and tight timelines
MBA, MHA, or similar advanced degree
Prior involvement in large‑scale clinical operations (>200 FTEs or multi‑site systems)
The annual salary range for this position is $102,000.00-$170,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Position may be eligible for a discretionary variable incentive bonus
Parental Leave and Adoption Assistance
401(k) Retirement Plan
Basic Life & Supplemental Life
Health Savings Account, Dental/Vision & Dependent Care Flexible Spending Accounts
Short-Term & Long-Term Disability
Student Loan PayDown
Tuition Reimbursement, Personal Development & Learning Opportunities
Skills Development & Certifications
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Emergency Back-Up Childcare Program
Mobility Stipend
About Guidehouse
Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.
All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.
If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.
Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.
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Senior Patient Safety Investigator
Job Family:
Technology Consulting
Travel Required:
Up to 10%
Clearance Required:
Ability to Obtain Public Trust
What You Will Do:
The Senior Patient Safety Investigator plays a critical role in establishing and operating a national patient safety function capable of managing a high volume of incoming and in‑flight safety complaints while driving systemic learning and long‑term improvement.
This role sits at the “middle” of the patient safety lifecycle—bridging intake and triage with investigation, escalation, closure, and post‑case learning. The individual will apply deep clinical judgment, standardized safety processes, and data‑driven insight to ensure that complaints are addressed consistently, escalated appropriately, and translated into actionable policy and operational improvements.
Intake, Triage & Case Management
Receive and acknowledge patient safety complaints from multiple intake channels (member‑submitted, patient‑submitted, call center, web‑based)
Conduct rapid clinical triage (often within 24 hours) to assess urgency and potential patient risk
Apply standardized risk stratification (high / moderate / low) using defined clinical and operational criteria
Identify duplicate or related complaints and ensure appropriate case linkage
Serve as case owner, maintaining accountability from intake through closure
Investigation & Escalation
Perform clinically grounded investigations, including:
Review of clinical narratives and supporting documentation
Identification of systemic versus isolated issues
Execute defined escalation pathways, including:
Internal leadership notification
Formal inquiries
Referral to MPSC or other oversight bodies as appropriate
Clearly document findings, decisions, and rationale within the case management system
Process & Program Development
Operationalize standardized patient safety workflows while recognizing the unique nature of individual cases
Help define and refine: Triage criteria, escalation thresholds and case closure standards
Support transition strategies for legacy cases, including close‑out approaches and intake of new complaints into modern systems
Learning, Feedback & Policy Improvement
Contribute to formal post‑case feedback loops to identify trends, recurring risks, and systemic gaps
Translate aggregated case insights into: Policy recommendations, Updated guidance and training or communication needs
Support transparency and leadership reporting to strengthen public trust in the OPTN patient safety function
Technology & Data Enablement
Actively use and help shape a case management platform
Ensure accurate, timely documentation to support: Workflow tracking, dashboards and leadership reporting and prevention of cases falling through the cracks
Partner with technology teams to ensure clinical workflows are reflected accurately in system design
Maintain strict compliance with HIPAA, PHI/PII handling, and federal security requirements
What You Will Need:
Registered Nurse (RN) required; advanced clinical leadership experience strongly preferred
10+ years of progressive clinical experience in acute care, perioperative, critical care, transplant, or related high‑acuity environments
Demonstrated experience exercising independent clinical judgment in complex, high‑risk situations
Proven experience in: Patient safety investigations, quality improvement and risk management or compliance.
Ability to assess clinical risk rapidly and consistently across diverse scenarios
Experience balancing standardized processes with case‑specific nuance
Experience working with EHRs and/or case management systems
Ability to adopt and help operationalize new technology platforms
Comfort using dashboards, reports, and structured data to support leadership decision‑making.
What Would Be Nice To Have:
Experience with organ donation, transplant services, or OPO operations
Prior work in federally regulated or oversight environments
Experience standing up new programs, workflows, or operating models
Experience leading or managing multidisciplinary clinical teams
Strong documentation, decision‑making, and escalation skills
Comfort operating in environments with high case volume and competing priorities
Ability to function effectively with limited external resourcing and tight timelines
MBA, MHA, or similar advanced degree
Prior involvement in large‑scale clinical operations (>200 FTEs or multi‑site systems)
The annual salary range for this position is $102,000.00-$170,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Position may be eligible for a discretionary variable incentive bonus
Parental Leave and Adoption Assistance
401(k) Retirement Plan
Basic Life & Supplemental Life
Health Savings Account, Dental/Vision & Dependent Care Flexible Spending Accounts
Short-Term & Long-Term Disability
Student Loan PayDown
Tuition Reimbursement, Personal Development & Learning Opportunities
Skills Development & Certifications
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Emergency Back-Up Childcare Program
Mobility Stipend
About Guidehouse
Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.
Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.
If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.
All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.
If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.
Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.
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Guidehouse · USA
Clinical Denial Specialist
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Inpatient Medical Coder
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